Crestor (rosuvastatin calcium) is a prescription strength synthetic lipid-lowering agent manufactured and marketed by AstraZeneca U.S. It belongs to a class of drugs called HMG-CoA reductase inhibitors (statins) that are designed to lower the bad cholesterol (LDL) and triglycerides (TG) levels in the blood stream. The active ingredient in Crestor is Rosuvastatin calcium, and the inactive ingredients are: microcrystalline cellulose NF, lactose monohydrate NF, tribasic calcium phosphate NF, crospovidone NF, magnesium stearate NF, hypromellose NF, triacetin NF, titanium dioxide USP, yellow ferric oxide, and red ferric oxide NF. Crestor can be taken as a single dose at any time of day with or without food. However, taking it with food does decrease the absorption. The FDA-approved tablet doses for oral administration are 5, 10, 20, and 40 mg. The 80 mg dosage was not approved.